Yang, Yan-Chang Huang, Yu-Ting Hsieh, Chia-Wen Yang, Po-Min Wung, Being-Sun HO-1 modulates CO-induced STAT3 glutathionylation. <p><b>A.</b> ECs were transiently transfected with pcDNA vector or HO-1 plasmid. S-glutathionylated STAT3 was immunoprecipitated and detected using a protein-SSG antibody. *<i>P</i><0.05 compared with untreated ECs. <b>B.</b> ECs were transfected with control or HO-1 siRNA vectors for 36 hours and then exposed to TCDC or MC for 12 hours. S-glutathionylated STAT3 was then detected as above. *<i>P</i><0.05 compared with untreated ECs. <sup>#</sup><i>P</i><0.05 compared with TCDC or MC alone.</p> anatomy;biological tissue;epithelium;Epithelial cells;Endothelial cells;Cardiovascular anatomy;cell biology;Cell processes;Cellular stress responses;Signal transduction;cell signaling;Signaling cascades;Stress signaling cascade;Redox signaling;STAT signaling;Mechanisms of signal transduction;Cellular types;Molecular cell biology;cardiology;Cardiovascular pharmacology;modulates;co-induced;stat3 2014-07-29
    https://plos.figshare.com/articles/figure/_HO_1_modulates_CO_induced_STAT3_glutathionylation_/1121371
10.1371/journal.pone.0100677.g008