TY - DATA T1 - Histopathology of the lung following 1.25×104Orientia challenge. PY - 2014/07/10 AU - Thomas R. Shelite AU - Tais B. Saito AU - Nicole L. Mendell AU - Bin Gong AU - Guang Xu AU - Lynn Soong AU - Gustavo Valbuena AU - Donald H. Bouyer AU - David H. Walker UR - https://plos.figshare.com/articles/figure/_Histopathology_of_the_lung_following_1_25_10_4_Orientia_challenge_/1099514 DO - 10.1371/journal.pntd.0002966.g007 L4 - https://ndownloader.figshare.com/files/1587779 KW - anatomy KW - histology KW - Histological examination KW - Respiratory system KW - lungs KW - liver KW - Computational biology KW - Population modeling KW - Infectious disease modeling KW - immunology KW - immunochemistry KW - microbiology KW - Animal models of infection KW - Infectious diseases KW - Bacterial diseases KW - typhus KW - Scrub typhus KW - Emerging infectious diseases KW - Tropical diseases KW - neglected tropical diseases N2 - H & E stained uninfected lung tissue (A-20×) and IHC of uninfected lung (B-40×) compared with lung from i.p. inoculated mice 12 dpi (H&E C-20×, IHC D-40×), and lung from i.v. inoculated 15 dpi (H&E E-20×, IHC F-40×). All i.p. infections were lethal with less severe pulmonary cellular infiltrate when compared to that of i.v. infected mice with capillary endothelial cell infection of the aveolar septa. ER -