%0 Figure %A R. Shelite, Thomas %A B. Saito, Tais %A L. Mendell, Nicole %A Gong, Bin %A Xu, Guang %A Soong, Lynn %A Valbuena, Gustavo %A H. Bouyer, Donald %A H. Walker, David %D 2014 %T Histopathology of the lung following 1.25×104Orientia challenge. %U https://plos.figshare.com/articles/figure/_Histopathology_of_the_lung_following_1_25_10_4_Orientia_challenge_/1099514 %R 10.1371/journal.pntd.0002966.g007 %2 https://ndownloader.figshare.com/files/1587779 %K anatomy %K histology %K Histological examination %K Respiratory system %K lungs %K liver %K Computational biology %K Population modeling %K Infectious disease modeling %K immunology %K immunochemistry %K microbiology %K Animal models of infection %K Infectious diseases %K Bacterial diseases %K typhus %K Scrub typhus %K Emerging infectious diseases %K Tropical diseases %K neglected tropical diseases %X

H & E stained uninfected lung tissue (A-20×) and IHC of uninfected lung (B-40×) compared with lung from i.p. inoculated mice 12 dpi (H&E C-20×, IHC D-40×), and lung from i.v. inoculated 15 dpi (H&E E-20×, IHC F-40×). All i.p. infections were lethal with less severe pulmonary cellular infiltrate when compared to that of i.v. infected mice with capillary endothelial cell infection of the aveolar septa.

%I PLOS Neglected Tropical Diseases