10.1371/journal.pone.0095256.g004 Evgeny Makarev Evgeny Makarev Marat Gorivodsky Marat Gorivodsky Cell proliferation in the crypt. Public Library of Science 2014 anatomy histology cell biology Signal transduction cell signaling Transcriptional signaling Molecular cell biology developmental biology genetics gene expression DNA transcription Gastroenterology and hepatology Model organisms Animal models Mouse models proliferation 2014-04-22 09:40:20 Figure https://plos.figshare.com/articles/figure/_Cell_proliferation_in_the_crypt_/1072428 <p>Cell proliferation is evaluated with antibodies for Ki-67 antigen. Cells expressing Ldb1 (a–c) and Isl1 (d–f) are negatively stained by Ki-67 proliferation marker. <b>a</b>. Ldb1-expressing cells (green); <b>b</b>. Ki-67-expressing proliferative cells (red); <b>c</b>. Merge of <b>a</b> and <b>b</b> (x1000). <b>d</b>. Isl1-expressing cells (red); <b>e</b>. Ki-67-expressing cells (green); <b>f</b>. Merge of <b>d</b> and <b>e</b> (x1000). Arrows point on cells expressing either Ldb1 (a, b, c) or Isl1 (d, e, f). Nuclei are counterstained with DAPI (blue).</p>