TY - DATA T1 - Prepulse inhibition of the startle response and radioligand binding assays PY - 2014/06/27 AU - Jerry Skefos AU - Melissa Ghulam AU - Arjun Mahendra AU - Gaurang Patel AU - Jose Larrauri AU - Ehsan Kholdebarin AU - Edward D. Levin AU - Margaret L. Bauman UR - https://f1000.figshare.com/articles/dataset/Prepulse_inhibition_of_the_startle_response_and_radioligand_binding_assays/1060215 DO - 10.6084/m9.figshare.1060215.v1 L4 - https://ndownloader.figshare.com/files/1538181 L4 - https://ndownloader.figshare.com/files/1538182 KW - prepulse inhibition KW - histaminergic H1 receptors KW - nicotinic α7 receptors KW - dizocilpine KW - pyrilamine KW - sensorimotor gating KW - Neuroscience N2 - Dataset 1. PPI data.The percent PPI data is provided for each prepulse decibel level tested. This raw behavioral data reflects the percentage of inhibition in prepulse-pulse trials compared with pulse-only trials for each prepulse intensity tested. The data is graphically presented in Figure 2. Dataset 2. Regional radioligand binding data.The radioligand binding data presented in Figures 3 – 7 is provided in fmol/mg tissue equivalent. In a few instances, tissue damage during processing prevented reliable densitometry within a region. These data were omitted from the study (indicated by blank cells in the spreadsheet). Additionally, we were unable to block nonspecific binding in all tissue samples from rat O0 for either radioligand, possibly due to tissue damage that was isolated to this case, so this data were omitted as well. AC = anterior cingulate, IC = insular cortex.   ER -