Power of the methods for scenarios with one of three traits associated with the QTL (A), two of three traits associated with the QTL (B) and with all three traits associated with the QTL (C).
Tessel E. Galesloot
Kristel van Steen
Lambertus A. L. M. Kiemeney
Luc L. Janss
Sita H. Vermeulen
10.1371/journal.pone.0095923.g002
https://plos.figshare.com/articles/figure/_Power_of_the_methods_for_scenarios_with_one_of_three_traits_associated_with_the_QTL_A_two_of_three_traits_associated_with_the_QTL_B_and_with_all_three_traits_associated_with_the_QTL_C_/1006599
<p>The explained variance of the QTL was fixed at 0.1%. For clarity reasons, we have not provided errors bars. Confidence ranges for the power estimates are all between 1 and 5%; exact values are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0095923#pone.0095923.s003" target="_blank">Tables S3</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0095923#pone.0095923.s005" target="_blank">S5</a>. MAF, minor allele frequency; MV, multivariate; PCHAT, Principal Component of Heritability Association Test; QTL, quantitative trait locus; rE, residual correlation; rG, genetic correlation induced by the QTL; TATES, Trait-based Association Test that uses Extended Simes procedure; UV-MA, meta-analysis of univariate results; UV-PCA, univariate analysis of first principal component; UV T1, univariate analysis of trait 1; UV T2, univariate analysis of trait 2; UV T3, univariate analysis of trait 3.</p>
2014-04-24 02:50:17
Computational biology
genome analysis
Genome-wide association studies
Evolutionary biology
population genetics
Genetic polymorphism
genetics
Human genetics
software engineering
Software tools
mathematics
Statistics (mathematics)
Biostatistics
Statistical methods
methods
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