(A) Kidney from wild type and (B) Eker rats were harvested at 12 months

Kidney from wild type rat show normal size and appearing while large size and multiple tumors were appeared in kidney of Eker rat. H&E staining of kidney from (C) wild type and (D) Eker rats. Kidney section of wild type and Eker rats shows normal tubular architecture of kidney in wild type rat and fibrovascular stroma (indicated by one head arrow) with clear cytoplasm and excentric in large nuclei of clear cell carcinoma type (indicated by two head arrow) in Eker rat.<p><b>Copyright information:</b></p><p>Taken from "Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors"</p><p>http://www.molecular-cancer.com/content/7/1/10</p><p>Molecular Cancer 2008;7():10-10.</p><p>Published online 24 Jan 2008</p><p>PMCID:PMC2265742.</p><p></p>