Strong selective sweeps on the X chromosome in the human-chimpanzee ancestor explain its low divergence
* CoalHMM estimates in 1Mb chunks
ILS09_gamma_aln_coord_clean_fixscale.csv
Estimates for the full genome alignment obtained as described in Nature. 2012 Mar 7;483(7388):169-75. doi: 10.1038/nature10842.
* Alignment statistics for the X chromosome
chrX.statistics.csv
This file has been generated by MafFilter on the the human, chimpanzee, gorilla and orangutan alignment. It contains counts on the various parsimony-informative sites.
* ILS in 100 kb windows along the genome alignment.
full_scan_100k.csv
ILS computed by window scanning along the posterior decoding from the CoalHMM method.
* Divergence ratios computed along the X chromosome.
Compara.epo_6_primates_hsap-projected.chrXnew.subset.nogap.cleaned_aln.statistics.csv
This file was generated by MafFilter on the X chromosome alignment. It contains the divergence estimates between human, chimpanzee, gorilla and orangutan in 100 kb windows.
* Nucleotide diversity for the X chromosome in 14 human populations
piX_100kb_regions.csv
This file was generated from the 1000 Human Genomes Project data.
* Genome coordinates of the 8 low-ILS regions
PNILSR_1Mb_10pc_edited.csv
Coordinates are according to human hg19.
* Coordinates of regions devoid of neanderthal introgression (Asian population)
Neanderthal_ASN.csv
Coordinates are according to human hg19.
* Coordinates of regions devoid of neanderthal introgression (European population)
Neanderthal_EUR.csv
Coordinates are according to human hg19.
* Ampliconic regions
AmpliconicRegions_hg19.csv
Ampliconic regions in hg19 coordinates. The two last column describe is the region was included in our genome alignment, and if it was comprised in a low-ILS region.