Whole genome expression analysis reveals down-regulated immune response genes and up-regulated detoxification genes during resolution of acute S. enterica infection.

(A) Flowchart of animal cohorts collected for the microarray analysis. (B) Gene ontology analysis of genes regulated during recovery at the 96 and 120 hour time points using the DAVID Bioinformatics Database. Enrichment scores of the 96-hour and 120-hour down-regulated clusters are shown in the left panel. Enrichment scores of the 96-hour and 120-hour up-regulated clusters are shown in the right panel. (C) Venn diagrams showing the overlap of the 96-hour and 120-hour down-regulated genes, left, and overlap of the 96-hour and 120-hour up-regulated genes, right. Representation factors are 43.5 and 64.3, respectively.