Figure_8.tif (217.03 kB)
Nanomolar amounts of aPC are required to degrade fVIII activity.
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posted on 2014-06-12, 03:07 authored by James E. Campbell, Michael Adam Meledeo, Andrew P. CapIn fresh PFP, no change in fVIII activity by aPC was observed until a dose >10 nM (p<0.001). fVdp showed a similar trend (p<0.05 that 3.3 nM and 100 nM aPC are different); fVIIIdp was used as a negative control. The mean and standard deviation of four PFP samples is shown; fVdp and fVIIIdp are means and standard deviations of two technical replicates.
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anatomyBody fluidsbloodplateletsBiochemistryproteinsCoagulation factorsPlasma proteinscardiologyAcute cardiovascular problemsDiagnostic medicineClinical laboratory sciencesTransfusion medicineCritical care and emergency medicineresuscitationhematologyBlood coagulationCoagulation disordersamountsapcdegradefviii
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