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Enhanced SIRT1 deacetylase activity in heart tissues from the mice treated i.p. with single dose of resveratrol (RSV, 5 mg/kg) or sildenafil (SIL, 0.7 mg/kg) for 24 hours (Graph A); *P<0.001 vs. Saline (n = 3/group).

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posted on 2014-01-22, 02:54 authored by Mona Shalwala, Shu-Guang Zhu, Anindita Das, Fadi N. Salloum, Lei Xi, Rakesh C. Kukreja

Graph B shows SIRT1 deacetylase activity in isolated cardiomyocytes following 1(1 µM, n = 3/group) in vitro. *P<0.05 vs. the untreated control group.

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