Figure_1.tif (585.35 kB)
Effects of Mpe and L-Dopa on lifespan.
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posted on 2014-10-23, 03:28 authored by Simone Poddighe, Francescaelena De Rose, Roberto Marotta, Roberta Ruffilli, Maura Fanti, Pietro Paolo Secci, Maria Cristina Mostallino, Maria Dolores Setzu, Maria Antonietta Zuncheddu, Ignazio Collu, Paolo Solla, Francesco Marrosu, Sanjay Kasture, Elio Acquas, Anna Liscia(A): Lifespan, expressed as % survival rates, of wild type (WT) and PINK1B9 flies. (B) and (C): Lifespan of PINK1B9 treated with Mucuna pruriens extract (Mpe) 0.1%,only when adults (L−/A+) (panel B) or from their larval stage to the end of their life-cycle (L+/A+) (panel C), respectively, as compared to lifespan of untreated PINK1B9 flies. (D): Lifespan of PINK1B9 flies treated with L-Dopa (L+/A+) 0.01%. *indicates p<0.05 at Kaplan-Meier survival curves (Gehan-Breslow–Wilcoxon - GraphPad Prism 5.01) between WT and untreated PINK1B9 (A) and between untreated PINK1B9 and PINK1B9 fed Mpe 0.1% (C).
