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DEK contributes to the proliferation of the colorectal cancer cell line, SW-620.

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posted on 2014-10-23, 03:30 authored by Lijuan Lin, Junjie Piao, Yibing Ma, Tiefeng Jin, Chengshi Quan, Jienan Kong, Yulin Li, Zhenhua Lin

(A) MTT assay showed the siDEK (100 nM) mimics significantly reduced the proliferation of SW-620 cells relative to the siControl group (P = 0.034). (B) MTT assay after 24 h, 48 h, 72 h and 96 h for siControl and siDEK-transfected SW-620 cells, *P<0.05, respectively. (C) Colony formation assay showed siDEK treatment inhibited colony formation in SW-620 cells by about 70% (P<0.001).

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