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Pelopuradazole, a new imidazole derivative alkaloid from the marine bacteria Pelomonas puraquae sp. nov.

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Version 2 2014-04-23, 07:27
Version 1 2014-04-23, 07:27
journal contribution
posted on 2014-04-23, 07:27 authored by Xi-Xin He, Xiao-Jie Chen, Guang-Tian Peng, Shan-Yue Guan, Ling-Fang Lei, Jun-Hua Yao, Bing-Xin Liu, Cui-Xian Zhang

One new imidazole derivative alkaloid pelopuradazole (1), together with three known alkaloids as in 3H-imidazole-4-carboxylic acid (2), 1H-pyrrole-2-carboxylic acid (3) and 2-methyl-3H-imidazole-4-carboxylic acid (4) and two known cyclo-dipeptides pelopurin A (5) and pelopurin B (6), has been isolated from the marine bacterium Pelomonas puraquae sp. nov. Pelopuradazole (1) was a new imidazole derivative alkaloid, while compounds 2, 3, 5 and 6 were firstly obtained as natural products. Compounds 16 were isolated from P. puraquae sp. nov. for the first time.

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