PCR-based alternative for diagnosis of immunoglobulin heavy chain gene rearrangement: principles, practice, and polemics
PCR-based detection of immunoglobulin gene rearrangements is a reliable and accurate method which can be utilized as a clinical test if appropriate quality controls are performed (internal, polyclonal and monoclonal, sensitivity and specificity controls) and strict criteria for clonal rearrangements are used to exclude false-positives and false-negatives.
You must be logged in to post comments.
You claim request was sent. I will be handled in the next 24 hours.Close window