Mitigating effects of vaccination given constraints in supply and daily administration capacity
Influenza viruses are a major cause of morbidity and mortality worldwide. Vaccination is a powerful tool for preventing or mitigating influenza outbreaks. Yet, vaccine supplies and daily administration capacities are limited, even in developed countries. Understanding how such constraints can alter the mitigating effects of vaccination is a crucial part of influenza preparedness plans. We present a mathematical model that explicitly takes into account vaccine supply and the number of vaccines administered per day and places data-informed limits on these parameters. We use the model to test several vaccination scenarios. The model can be used by government and medical officials to create customized pandemic preparedness plans based on the supply and administration constraints of specific communities.
This work was published in full in Cruz-Aponte, M., McKiernan, E. C. and Herrera-Valdez, M. A. (2011). Mitigating effects of vaccination on influenza outbreaks given constraints in stockpile size and daily administration capacity. BMC Infectious Diseases 11(1), 207 (DOI below).
This fileset includes: (1) a poster presented at the 32nd Annual Research and Education Forum held at the University of Puerto Rico, Medical Sciences campus (pdf), (2) the tex file used to generate the pdf, which can serve as a LaTeX poster template, (3) the bibtex file with references from the published article, and (4) all figures presented in the poster.
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