Is this bilayer expansion?

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Perlstein, Ethan; Korostyshevsky, Daniel (2012): Is this bilayer expansion?. figshare.
Retrieved 04:11, Jul 28, 2014 (GMT)


A clathrin heavy chain (chc1) mutant that is resistant to the SSRI antidepressant sertraline/Zoloft exhibits what appears to be bilayer expansion under both steady state and sertraline-treated conditions. It is also possible that the expansion of electron lucent (that is, white) material is occurring inside the lumen of amphisomes (aka autophagolysosomes).

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