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Green, One-Pot, Multicomponent Synthesis of Fused-Ring 2-Aminothiazoles

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Version 4 2014-11-05, 18:09
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journal contribution
posted on 2014-11-05, 18:09 authored by Siddique Anwar, Satya B. Paul, K. C. Majumdar, Sudip Choudhury

A facile, green, and efficient Fe(III) chloride, one-pot, multicomponent reaction (MCR) for synthesis of 2-aminothiazole-based compounds is reported. Considering the medicinal importance of fused ring 2-aminothiazoles, this process provides an easy route to the synthesis of this class of compound. Detailed mechanism of the reaction has been discussed.

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